Article
Temporal changes in peritoneal cell phenotype and neoelastic matrix induction with hyaluronan oligomers and TGF-β1 after implantation of engineered conduits.
Journal of tissue engineering and regenerative medicine - 1 Jun 2018
Shojaee Mozhgan, Swaminathan Ganesh, Bashur Chris A, Ramamurthi Anand
Abstract excerpt
The neoassembly and maturation of elastic matrix is an important challenge for engineering small-diameter grafts for patients with peripheral artery disease. We have previously shown that hyaluronan oligomers and transforming growth factor-β (elastogenic factors or EFs) promote elastogenesis in smooth muscle cell (SMC) culture. However, their combined effects on macrophages and inflammatory cells in vivo are...
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