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Article

SynCAM 1 improves survival of adult-born neurons by accelerating synapse maturation.

Hippocampus - 1 Mar 2016

Doengi Michael, Krupp Alexander J, Körber Nils, Stein Valentin

Abstract excerpt

The survival of adult-born dentate gyrus granule cells critically depends on their synaptic integration into the existing neuronal network. Excitatory inputs are thought to increase the survival rate of adult born neurons. Therefore, whether enhancing the stability of newly formed excitatory synapses by overexpressing the synaptic cell adhesion molecule SynCAM 1 improves the survival of adult-born neurons was...

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PMID: 26332750
DOI: 10.1002/hipo.22524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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