Article
Developmental increase of asynchronic glutamate release from hippocampal synapses in mutant taiep rat.
Synapse (New York, N.Y.) - 1 Jun 2009
Fuenzalida Marco, Aliaga Esteban, Olivares Virginia, Roncagliolo Manuel, Bonansco Christian
Abstract excerpt
During development, regulation of the strength of synaptic transmission plays a central role in the formation of mammalian brain circuitries. In taiep rat, a neurological mutant with severe reactive astrogliosis and demyelination, we have described alterations in the synaptic transmission in central neurons, characterized by asynchronous excitatory postsynaptic currents ((ASYN)EPSCs), because of delayed...
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