Article
Temporally distinct demands for classic cadherins in synapse formation and maturation.
Molecular and cellular neurosciences - 1 Dec 2004
Bozdagi Ozlem, Valcin Martin, Poskanzer Kira, Tanaka Hidekazu, Benson Deanna L
Abstract excerpt
Classic cadherins are synaptic adhesion proteins that have been implicated in synapse formation and targeting. Brief inactivation of classic cadherin function in young neurons appears to abrogate synapse formation when examined acutely. It remains unknown if such abrogation is unique to young neurons, whether it occurs by stalling neuronal maturation or by directly interfering with the process of synapse...
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