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Article

High Prevalence of inhA Promoter Mutations among Patients with Drug-Resistant Tuberculosis in KwaZulu-Natal, South Africa.

PloS one - 1 Jan 2015

Niehaus Abraham J, Mlisana Koleka, Gandhi Neel R, Mathema Barun, Brust James C M

Abstract excerpt

BACKGROUND: Drug-resistant tuberculosis (TB) remains extremely difficult to treat because there are often few remaining active medications and limited diagnostic options to detect resistance. Resistance to isoniazid is typically caused by mutations in either katG or the inhA promoter. inhA mutati...

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PMID: 26332235
DOI: 10.1371/journal.pone.0135003
PMCID: PMC4557915

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LPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26332235-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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