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Article

inhA promoter mutations: a gateway to extensively drug-resistant tuberculosis in South Africa?

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Mar 2011

Müller B, Streicher E M, Hoek K G P, Tait M, Trollip A, Bosman M E, Coetzee G J, Chabula-Nxiweni E M, Hoosain E, Gey van Pittius N C, Victor T C, van Helden P D, Warren R M

Abstract excerpt

SETTING: Western Cape and Eastern Cape Provinces, South Africa. OBJECTIVE: To assess the potential association between the evolution of extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis and mutations in the inhA promoter or the katG gene. DESIGN: Analysis of the frequency distribution of isoniazid (INH) resistance conferring mutations in a population sample of drug-resistant isolates of M....

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PMID: 21333101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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