Article
Detection of katG and inhA mutations to guide isoniazid and ethionamide use for drug-resistant tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Aug 2016
Bollela V R, Namburete E I, Feliciano C S, Macheque D, Harrison L H, Caminero J A
Abstract excerpt
BACKGROUND: Depending on the presence of mutations that determine isoniazid (INH) susceptibility (katG and inhA), Mycobacterium tuberculosis may be susceptible to high doses of INH or ethionamide (ETH). OBJECTIVE: To describe the INH resistance profile and association of katG mutation with previous INH treatment and level of drug resistance based on rapid molecular drug susceptibility testing (DST) in southern...
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