Article
Visual evoked potentials detect cortical processing deficits in Rett syndrome.
Annals of neurology - 1 Nov 2015
LeBlanc Jocelyn J, DeGregorio Geneva, Centofante Eleonora, Vogel-Farley Vanessa K, Barnes Katherine, Kaufmann Walter E, Fagiolini Michela, Nelson Charles A
Abstract excerpt
OBJECTIVE: Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutation of the X-linked MECP2 gene and characterized by developmental regression during the first few years of life. The objective of this study was to investigate if the visual evoked potential (VEP) could be used as an unbiased, quantitative biomarker to monitor brain function in RTT. METHODS: We recorded pattern-reversal VEPs in Mecp2...
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