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Article

CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells.

Molecular carcinogenesis - 1 Nov 2016

Lee Woan-Ruoh, Shen Shing-Chuan, Wu Pei-Ru, Chou Chia-Lun, Shih Yi-Hsien, Yeh Chung-Min, Yeh Kun-Tu, Jiang Ming-Chung

Abstract excerpt

The Ras/ERK (extracellular signal-regulated protein kinase) and cAMP/PKA (protein kinase A) pathways are essential for the transcriptional activities of CREB (cAMP response element binding protein) and MITF (microphthalmia-associated transcription factor) in melanogenesis and the progression of melanoma. However, the interaction between Ras/ERK and cAMP/PKA pathways in the melanogenesis and progression of...

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Source

Identifiers

PMID: 26331446
DOI: 10.1002/mc.22407

Genes

MITF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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