Article
MicroRNA-379 mediates pigmentation, migration and proliferation of melanocytes by targeting the insulin-like growth factor 1 receptor.
Experimental dermatology - 1 May 2020
Liu Bo, Zhang Junzhen, Hu Shixiong, Qi Shuhui, Jia Qiong, Yang Wanyun, Yang Shanshan, Ji Kaiyuan, Liu Xuexian, Dong Changsheng, Fan Ruiwen
Abstract excerpt
Melanogenesis, migration and proliferation of melanocytes are important factors that determine the hair colours of mammals. MicroRNAs (miRNAs) have been shown to be closely related to these processes. In melanocytes of alpacas, insulin-like growth factor 1 (IGF1) has been shown to improve melanogenesis through the cyclic AMP (cAMP) pathway. miR-379 was predicted to target insulin-like growth factor (IGF) receptor...
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