Article
CD4(+)CD25(High) Treg cells in HIV/HTLV co-infected patients with neuropathy: high expression of Alpha4 integrin and lower expression of Foxp3 transcription factor.
BMC immunology - 2 Sept 2015
Matavele Chissumba Raquel, Silva-Barbosa Suse Dayse, Augusto Ângelo, Maueia Cremildo, Mabunda Nédio, Gudo Eduardo Samo, Bhatt Nilesh, Jani Ilesh, Savino Wilson
Abstract excerpt
BACKGROUND: Regulatory CD4 T cells (Tregs) are critical in maintaining the homeostasis of the immune system. Quantitative or phenotypic alterations and functional impairment of Tregs have been associated with the development of pathologies including those of the central nervous system. Individual...
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