Article
Gamma-Delta T-Cell Phenotype and Function in DAA-Treated HIV-HCV Co-Infected and HCV-Mono-Infected Subjects.
Viruses - 22 Jul 2022
Bono Valeria, Tincati Camilla, Van Den Bogaart Lorena, Cannizzo Elvira Stefania, Rovito Roberta, Augello Matteo, De Bona Anna, D'Arminio Monforte Antonella, Milazzo Laura, Marchetti Giulia
Abstract excerpt
HIV-HCV co-infected subjects are at risk of liver fibrosis which may be linked to immune imbalances. Direct-acting antivirals (DAAs) represent the mainstay of HCV treatment in co-infected individuals, yet their effects on immune cell populations playing a role in fibrogenesis is unknown. We assessed γδ T-cell phenotype and function, Treg and Th17 frequencies, as well as γ-globulins and B-cell activation in 47...
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