Article
Nanotechnology as a New Therapeutic Approach to Prevent the HIV-Infection of Treg Cells.
PloS one - 1 Jan 2016
Jaramillo-Ruiz Didiana, De La Mata Francisco Javier, Gómez Rafael, Correa-Rocha Rafael, Muñoz-Fernández M Ángeles
Abstract excerpt
BACKGROUND: HIV-1 has proved to infect regulatory T cells (Treg) modifying their phenotype and impairing their suppressive capacity. As Treg cells are a crucial component in the preservation of the immune homeostasis, we researched that the antiviral capacity of carboxilan dendrimers prevents the HIV-1 infection of Treg and their effects. The phenotype and suppressive capacity of Treg treated or non-treated with...
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