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Article

Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy.

Oncotarget - 28 Aug 2015

Bennett Ailsa, Bechi Beatrice, Tighe Anthony, Thompson Sarah, Procter David J, Taylor Stephen S

Abstract excerpt

Aneuploidy is a common feature of cancer, with human solid tumour cells typically harbouring abnormal chromosome complements. The aneuploidy observed in cancer is often caused by a chromosome instability phenotype, resulting in genomic heterogeneity. However, the role aneuploidy and chromosome in...

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Identifiers

PMID: 26320186
DOI: 10.18632/oncotarget.4879
PMCID: PMC4673239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26320186-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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