Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The β3 subunit of the nicotinic acetylcholine receptor: Modulation of gene expression and nicotine consumption.

Neuropharmacology - 1 Dec 2015

Kamens Helen M, Miyamoto Jill, Powers Matthew S, Ro Kasey, Soto Marissa, Cox Ryan, Stitzel Jerry A, Ehringer Marissa A

Abstract excerpt

Genetic factors explain approximately half of the variance in smoking behaviors, but the molecular mechanism by which genetic variation influences behavior is poorly understood. SNPs in the putative promoter region of CHRNB3, the gene that encodes the β3 subunit of the nicotinic acetylcholine receptor (nAChR), have been repeatedly associated with nicotine behaviors. In this work we sought to identify putative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Temperature
Share to Choice Behavior

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HEK293 Cells

Share to Mice, 129 Strain

Share to Motor Activity

Share to Nicotine

Share to Nicotinic Agonists

Share to Receptors, Nicotinic

Source

Open in PubMed Open full text

Identifiers

PMID: 26318101
DOI: 10.1016/j.neuropharm.2015.08.035
PMCID: PMC4655151

Genes

CHRNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The β3 subunit of the nicotinic acetylcholine receptor: Modulation of gene expression and nicotine consumption.PMID 26318101Read ↗

Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumptionSemantic proximity Read ↗

Functional characterization improves associations between rare non-synonymous variants in CHRNB4 and smoking behavior.Semantic proximity Read ↗

Identification of rs2036527 as a cis-regulatory variant for CHRNA3 and CHRNA5 by allele-specific expression and implications for nicotine dependence and lung cancer.Semantic proximity Read ↗

CHRNB3 c.-57A>G functional promoter change affects Parkinson's disease and smoking.Semantic proximity Read ↗

Significant association of CHRNB3 variants with nicotine dependence in multiple ethnic populations.Semantic proximity Read ↗

Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample.Semantic proximity Read ↗

Rare coding variants in CHRNB2 reduce the likelihood of smoking.Semantic proximity Read ↗

Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans.Semantic proximity Read ↗

CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences.Semantic proximity Read ↗

From men to mice: CHRNA5/CHRNA3, smoking behavior and disease.Semantic proximity Read ↗

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.Semantic proximity Read ↗

Genetic susceptibility to nicotine addiction: Advances and shortcomings in our understanding of the CHRNA5/A3/B4 gene cluster contribution.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.