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Article

Effects of APOE promoter polymorphism on the topological organization of brain structural connectome in nondemented elderly.

Human brain mapping - 1 Dec 2015

Shu Ni, Li Xin, Ma Chao, Zhang Junying, Chen Kewei, Liang Ying, Chen Yaojing, Zhang Zhanjun

Abstract excerpt

The polymorphism of the Apolipoprotein E (APOE) promoter rs405509 can regulate the transcriptional activity of the APOE gene and is related to Alzheimer's disease (AD). However, its effects on cognitive performance and the underlying brain mechanisms remain unknown. Here, we performed a battery o...

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Identifiers

PMID: 26314833
DOI: 10.1002/hbm.22954
PMCID: PMC4715757

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26314833-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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