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Article

Association between TERT promoter polymorphisms and acute myeloid leukemia risk and prognosis.

Oncotarget - 22 Sept 2015

Mosrati Mohamed Ali, Willander Kerstin, Falk Ingrid Jakobsen, Hermanson Monica, Höglund Martin, Stockelberg Dick, Wei Yuan, Lotfi Kourosh, Söderkvist Peter

Abstract excerpt

Telomerase reverse transcriptase gene (TERT) promoter mutations are identified in many malignancies but not in hematological malignancies. Here we analyzed TERT and protection of telomeres 1 gene (POT1) mutations, and four different TERT SNVs in 226 acute myeloid leukemia (AML) patients and 806 healthy individuals in a case referent design, where also overall survival was assessed. A significant association for...

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Source

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Identifiers

PMID: 26298771
DOI: 10.18632/oncotarget.4668
PMCID: PMC4694818

Genes

TERT
POT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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