Article
TERT Genotype Polymorphism: A Glance of Change Egyptian MDS Outcomes.
Asian Pacific journal of cancer prevention : APJCP - 1 May 2021
El Menshawy Nadia, El-Ashwah Shaimaa, Ebrahim Mohamed A, Mortada Metwally Ibrahem, Ramez Ahmed, Attia Doaa M
Abstract excerpt
BACKGROUND: Myelodysplastic Syndromes (MDS)are clonal hematologic disorders characterized by genetic instability and ineffective hematopoiesis associated with telomere dysfunction. We aimed at investigating the association between the rs2242652 single nucleotide variant of the TERT gene and susceptibility for MDS, as well as its prognostic impact and relation to disease phenotype. METHODS: Genotyping analysis was...
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