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Article

Outcome after BCG treatment for urinary bladder cancer may be influenced by polymorphisms in the NOS2 and NOS3 genes.

Redox biology - 1 Dec 2015

Ryk Charlotta, Koskela Lotta Renström, Thiel Tomas, Wiklund N Peter, Steineck Gunnar, Schumacher Martin C, de Verdier Petra J

Abstract excerpt

PURPOSE: Bacillus Calmette-Guérin (BCG)-treatment is an established treatment for bladder cancer, but its mechanisms of action are not fully understood. High-risk non-muscle invasive bladder-cancer (NMIBC)-patients failing to respond to BCG-treatment have worse prognosis than those undergoing immediate radical cystectomy and identification of patients at risk for BCG-failure is of high priority. Several studies...

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Identifiers

PMID: 26298202
DOI: 10.1016/j.redox.2015.08.008
PMCID: PMC4556773

Genes

NOS2
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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