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Article

FASL polymorphism is associated with response to bacillus Calmette-Guérin immunotherapy in bladder cancer.

Urologic oncology - 1 Jan 2014

Lima Luís, Ferreira José A, Tavares Ana, Oliveira Daniela, Morais António, Videira Paula A, Medeiros Rui, Santos Lúcio

Abstract excerpt

OBJECTIVE: Deregulation of FAS/FASL system may lead to immune escape and influence bacillus Calmette-Guérin (BCG) immunotherapy outcome, which is currently the gold standard adjuvant treatment for high-risk non-muscle invasive bladder tumors. Among other events, functional promoter polymorphisms of FAS and FASL genes may alter their transcriptional activity. Therefore, we aim to evaluate the role of FAS and FASL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23948181
DOI: 10.1016/j.urolonc.2013.05.009

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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