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Article

Polymorphisms In The Nitric-Oxide Synthase 2 Gene And Prostate Cancer Pathogenesis.

Redox biology - 1 Aug 2015

Ryk Charlotta, de Verdier Petra, Montgomery Emmie, Peter Wiklund N, Wiklund Fredrik, Grönberg Henrik

Abstract excerpt

BACKGROUND: Nitric-oxide synthase (NOS)-polymorphisms influence the cellular amount of NO, and are associated with disease-risk in many disorders. We investigated 145 SNP-polymorphisms and a (CCTTT)n-microsatellite in the NOS2-gene in 3161 prostate-cancer patients and 2149 controls from a Swedish population-based GWAS-study. AIM: To analyze possible associations between NOS2-polymorphisms, prostate cancer, and...

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Identifiers

PMID: 28162285
DOI: 10.1016/j.redox.2015.09.029

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NOS2

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