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Article

Genetic polymorphisms in glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of southwestern Taiwan.

Journal of biomedical science - 29 Jul 2011

Hsu Ling-I, Chen Wu-Ping, Yang Tse-Yen, Chen Yu-Hsin, Lo Wann-Cheng, Wang Yuan-Hung, Liao Ya-Tang, Hsueh Yu-Mei, Chiou Hung-Yi, Wu Meei-Maan, Chen Chien-Jen

Abstract excerpt

BACKGROUND: Arsenic exposure is an important public health issue worldwide. Dose-response relationship between arsenic exposure and risk of urothelial carcinoma (UC) is consistently observed. Inorganic arsenic is methylated to form the metabolites monomethylarsonic acid and dimethylarsinic acid while ingested. Variations in capacity of xenobiotic detoxification and arsenic methylation might explain individual...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21798077
DOI: 10.1186/1423-0127-18-51
PMCID: PMC3199751

Genes

GSTT1
GSTO1
GSTO2
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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