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Article

A case-control study of polymorphisms in xenobiotic and arsenic metabolism genes and arsenic-related bladder cancer in New Hampshire.

Toxicology letters - 5 Apr 2012

Lesseur Corina, Gilbert-Diamond Diane, Andrew Angeline S, Ekstrom Rebecca M, Li Zhongze, Kelsey Karl T, Marsit Carmen J, Karagas Margaret R

Abstract excerpt

Arsenic is associated with bladder cancer risk even at low exposure levels. Genetic variation in enzymes involved in xenobiotic and arsenic metabolism may modulate individual susceptibility to arsenic-related bladder cancer. Through a population-based case-control study in NH (832 cases and 1191...

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Source

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Identifiers

PMID: 22306368
DOI: 10.1016/j.toxlet.2012.01.015
PMCID: PMC3374400

Genes

AQP3
GSTO2
GSTP1
GSTZ1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22306368-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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