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Article

Association of XRCC1 polymorphisms with arsenic methylation.

Archives of toxicology - 1 Apr 2016

Fujihara Junko, Yasuda Toshihiro, Iwata Hisato, Tanabe Shinsuke, Takeshita Haruo

Abstract excerpt

The associations of four single nucleotide polymorphisms (p.Arg194Trp, p.Arg280His, p.Pro206Pro, and p.Arg399Gln) in X-ray repair cross-complementing group 1 with urinary arsenic metabolites and 8-hydroxy-2'-deoxyguanosine (8-OHdG) were investigated in a Vietnamese population (n = 100). Individuals with genotype AA in p.Pro206Pro showed significantly higher urinary monomethylarsonic acid (MMA(V)) and lower...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25731970
DOI: 10.1007/s00204-015-1490-0

Genes

XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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Association of XRCC1 polymorphisms with arsenic methylation.PMID 25731970Read ↗

X-ray repair cross-complementing group 1 polymorphisms and cancer risks in Asian populations: a mini review.Semantic proximity Read ↗

XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are associated with urothelial carcinoma.Semantic proximity Read ↗

Polymorphic trial in oxidative damage of arsenic exposed Vietnamese.Semantic proximity Read ↗

The polymorphism XRCC1 Arg194Trp and 8-hydroxydeoxyguanosine increased susceptibility to arsenic-related renal cell carcinoma.Semantic proximity Read ↗

Association of XRCC1 Arg399Gln polymorphism with bladder cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Genetic polymorphisms in glutathione S-transferase (GST) superfamily and arsenic metabolism in residents of the Red River Delta, Vietnam.Semantic proximity Read ↗

Meta-analysis demonstrates no association between XRCC1 Arg399Gln polymorphism and bladder cancer risk.Semantic proximity Read ↗

Genetic polymorphisms in AS3MT and arsenic metabolism in residents of the Red River Delta, Vietnam.Semantic proximity Read ↗

Association between X-ray repair cross-complementing group 1 Arg194Trp polymorphism and prostate cancer risk.Semantic proximity Read ↗

Implications of XRCC1, XPD and APE1 gene polymorphism in North Indian population: a comparative approach in different ethnic groups worldwide.Semantic proximity Read ↗

DNA repair gene polymorphisms at XRCC1 (Arg194Trp, Arg280His, and Arg399Gln) in a healthy Tunisian population: interethnic variation and functional prediction.Semantic proximity Read ↗

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