Article
Recognition deficits in mice carrying mutations of genes encoding BLOC-1 subunits pallidin or dysbindin.
Genes, brain, and behavior - 1 Nov 2015
Spiegel S, Chiu A, James A S, Jentsch J D, Karlsgodt K H
Abstract excerpt
Numerous studies have implicated DTNBP1, the gene encoding dystrobrevin-binding protein or dysbindin, as a candidate risk gene for schizophrenia, though this relationship remains somewhat controversial. Variation in dysbindin, and its location on chromosome 6p, has been associated with cognitive processes, including those relying on a complex system of glutamatergic and dopaminergic interactions. Dysbindin is one...
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