Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.

The Journal of investigative dermatology - 1 Dec 2015

Ando Noriko, Nakamura Yuki, Aoki Rui, Ishimaru Kayoko, Ogawa Hideoki, Okumura Ko, Shibata Shigenobu, Shimada Shinji, Nakao Atsuhito

Abstract excerpt

There are several reports suggesting that the pathophysiology of psoriasis may be associated with aberrant circadian rhythms. However, the mechanistic link between psoriasis and the circadian time-keeping system, "the circadian clock," remains unclear. This study determined whether the core circadian gene, Clock, had a regulatory role in the development of psoriasis. For this purpose, we compared the development...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminoquinolines
Share to Circadian Rhythm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CLOCK Proteins

Share to Dermatitis

Share to Interleukin-23

Share to Period Circadian Proteins

Share to Psoriasis

Share to Receptors, Antigen, T-Cell, gamma-delta

Source

Open in PubMed Open full text

Identifiers

PMID: 26291684
DOI: 10.1038/jid.2015.316
PMCID: PMC4653315

Genes

CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.PMID 26291684Read ↗

LiangxueJiedu Formula improves psoriatic dermatitis by regulating the circadian clock to inhibit IL-17-producing Th17 and γδT cellsSemantic proximity Read ↗

The skin circadian clock gene F3 as a potential marker for psoriasis severity and its bidirectional relationship with IL-17 signaling in keratinocytesSemantic proximity Read ↗

Circadian control of interferon-sensitive gene expression in murine skinSemantic proximity Read ↗

The skin circadian clock gene F3 as a potential marker for psoriasis severity and its bidirectional relationship with IL-17 signaling in keratinocytesSemantic proximity Read ↗

Psoriasis and Seasonality: Exploring the Genetic and Epigenetic Interactions.Semantic proximity Read ↗

Seasonality of Psoriasis: From Genes to the Clinical PhenomenaSemantic proximity Read ↗

An aging-susceptible circadian rhythm controls cutaneous antiviral immunitySemantic proximity Read ↗

Population level rhythms in human skin: implications for circadian medicineSemantic proximity Read ↗

Bioinformatics Integrative Analysis of Circadian Rhythms Effects on Atopic Dermatitis and Dendritic CellsSemantic proximity Read ↗

The circadian clock in skin: implications for adult stem cells, tissue regeneration, cancer, aging, and immunity.Semantic proximity Read ↗

PER, a Circadian Clock Component, Mediates the Suppression of MMP-1 Expression in HaCaT Keratinocytes by cAMPSemantic proximity Read ↗

Circadian gene period1b regulates proinflammatory cytokine expression through NF-κB signalling in zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.