Article

The skin circadian clock gene F3 as a potential marker for psoriasis severity and its bidirectional relationship with IL-17 signaling in keratinocytes

2024-01-01

Abstract excerpt

<h4>Background: </h4> Psoriasis is an immune-mediated skin disease where the IL-17 signaling pathway plays a crucial role in its development. Chronic circadian rhythm disorder in psoriasis pathogenesis is gaining more attention. The relationship between IL-17 signaling pathway and skin clock genes remains poorly understood. Methods GSE121212 with psoriatic lesion and healthy controls was used as exploration cohor...

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Literature Corpus work: 97e4eefa-a968-549e-ba8c-834b8f5650ed
DOI: 10.21203/rs.3.rs-3799546/v1

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