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Bioinformatics Integrative Analysis of Circadian Rhythms Effects on Atopic Dermatitis and Dendritic Cells

1 Oct 2023

Abstract excerpt

Background: Atopic dermatitis (AD) is an allergic inflammatory skin disease caused by aberrant and over-reactive immune response. Although circadian rhythm disruption is implicated in multiple immunoinflammatory conditions, including AD, the mechanisms at the molecular level underlying AD and circadian rhythms remain elusive. Methods: Bulk and single-cell RNA-sequencing data of AD patients were acquired from the...

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PMID: 37873510
DOI: 10.2147/ccid.s424343

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