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Article

The skin circadian clock gene F3 as a potential marker for psoriasis severity and its bidirectional relationship with IL-17 signaling in keratinocytes

1 Apr 2024

Abstract excerpt

OBJECTIVE: Psoriasis is an immune-mediated skin disease where the IL-17 signaling pathway plays a crucial role in its development. Chronic circadian rhythm disorder in psoriasis pathogenesis is gaining more attention. The relationship between IL and 17 signaling pathway and skin clock genes remains poorly understood. METHODS: GSE121212 with psoriatic lesion and healthy controls was used as the exploration cohort...

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Share to Circadian rhythm and melatonin
Share to Dermatology and Skin Diseases
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PMID: 38565044
DOI: 10.1016/j.intimp.2024.111993

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