Article
The circadian clock in skin: implications for adult stem cells, tissue regeneration, cancer, aging, and immunity.
Journal of biological rhythms - 1 Jun 2015
Plikus Maksim V, Van Spyk Elyse N, Pham Kim, Geyfman Mikhail, Kumar Vivek, Takahashi Joseph S, Andersen Bogi
Abstract excerpt
Historically, work on peripheral circadian clocks has been focused on organs and tissues that have prominent metabolic functions, such as the liver, fat, and muscle. In recent years, skin has emerged as a model for studying circadian clock regulation of cell proliferation, stem cell functions, tissue regeneration, aging, and carcinogenesis. Morphologically, skin is complex, containing multiple cell types and...
Topics
- Adult Stem Cells
- Animals
- Cell Proliferation
- Circadian Clocks
- Circadian Rhythm
- Humans
- Immunity
- Mutation
- Psoriasis
- Regeneration
- Skin
- Skin Aging
- Skin Neoplasms
- Skin Physiological Phenomena