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Article

Circadian control of interferon-sensitive gene expression in murine skin

4 Mar 2020

Abstract excerpt

The circadian clock coordinates a variety of immune responses with signals from the external environment to promote survival. We investigated the potential reciprocal relationship between the circadian clock and skin inflammation. We treated mice topically with the Toll-like receptor 7 (TLR7) agonist imiquimod (IMQ) to activate IFN-sensitive gene (ISG) pathways and induce psoriasiform inflammation. IMQ...

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Share to Circadian rhythm and melatonin
Share to Dermatology and Skin Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32132203
DOI: 10.1073/pnas.1915773117

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