Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PER, a Circadian Clock Component, Mediates the Suppression of MMP-1 Expression in HaCaT Keratinocytes by cAMP

23 Mar 2018

Abstract excerpt

Skin circadian clock system responds to daily changes, thereby regulating skin functions. Exposure of the skin to UV irradiation induces the expression of matrix metalloproteinase-1 (MMP-1) and causes DNA damage. It has been reported both DNA repair and DNA replication are regulated by the circadian clock in mouse skin. However, the molecular link between circadian clock and MMP-1 has little been investigated. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidant Activity and Oxidative Stress
Share to Circadian rhythm and melatonin
Share to Skin Protection and Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29570674
DOI: 10.3390/molecules23040745

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PER, a Circadian Clock Component, Mediates the Suppression of MMP-1 Expression in HaCaT Keratinocytes by cAMPPMID 29570674Read ↗

TIMP3 is a CLOCK‐dependent diurnal gene that inhibits the expression of UVB‐induced inflammatory cytokines in human keratinocytesSemantic proximity Read ↗

The Impact of the Circadian Clock on Skin Physiology and Cancer DevelopmentSemantic proximity Read ↗

Comparative circadian transcriptome analysis reveals dampened and phase-advanced rhythms in sun-exposed human skinSemantic proximity Read ↗

The circadian clock in skin: implications for adult stem cells, tissue regeneration, cancer, aging, and immunity.Semantic proximity Read ↗

Circadian effects on UV-induced damage and mutations.Semantic proximity Read ↗

LiangxueJiedu Formula improves psoriatic dermatitis by regulating the circadian clock to inhibit IL-17-producing Th17 and γδT cellsSemantic proximity Read ↗

Molecular Mechanisms of Photoaging in Human Skin In Vivo and Their Prevention by All-Trans Retinoic AcidSemantic proximity Read ↗

Circadian actin dynamics drive rhythmic fibroblast mobilization during wound healingSemantic proximity Read ↗

Time-Restricted Feeding Shifts the Skin Circadian Clock and Alters UVB-Induced DNA DamageSemantic proximity Read ↗

Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.Semantic proximity Read ↗

Circadian clock regulates epidermal endocrine system in homeostatic skin pigmentationSemantic proximity Read ↗

Population level rhythms in human skin: implications for circadian medicineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.