Article
Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease.
PloS one - 5 Nov 2009
Stark Klaus, Reinhard Wibke, Grassl Martina, Erdmann Jeanette, Schunkert Heribert, Illig Thomas, Hengstenberg Christian
Abstract excerpt
BACKGROUND: Recently, a large meta-analysis including over 28,000 participants identified nine different loci with association to serum uric acid (UA) levels. Since elevated serum UA levels potentially cause gout and are a possible risk factor for coronary artery disease (CAD) and myocardial infarction (MI), we performed two large case-control association analyses with participants from the German MI Family...
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