Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of irisin and FNDC5 rs16835198 G>T gene polymorphism with type 2 diabetes mellitus and diabetic nephropathy. An Egyptian pilot study.

Gene - 30 Aug 2017

Khidr Emad Gamil, Ali Shawkey Saddik, Elshafey Mostafa Mahmoud, Fawzy Olfat Ahmed

Abstract excerpt

Diabetes mellitus is a fast-growing health problem in Egypt affecting morbidity, mortality and health care resources. Irisin, a new exercise-induced myokine inducing browning of white adipose tissues, has gained a great interest as a potential new target for combating type 2 diabetes mellitus (T2DM) and its complications. In this study, we assessed serum irisin levels in T2DM and diabetic nephropathy to elucidate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetic Nephropathies

Share to Dyslipidemias

Share to Fibronectins

Share to Insulin Resistance

Share to Pilot Projects

Source

Identifiers

PMID: 28479383
DOI: 10.1016/j.gene.2017.05.010

Genes

FNDC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of irisin and FNDC5 rs16835198 G>T gene polymorphism with type 2 diabetes mellitus and diabetic nephropathy. An Egyptian pilot study.PMID 28479383Read ↗

Obesity and its Association with Irisin Level Among Individuals with FNDC5/Irisin Gene Variants RS16835198 and RS726344.Semantic proximity Read ↗

SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects.Semantic proximity Read ↗

Irisin-encoding gene (FNDC5) variant is associated with changes in blood pressure and lipid profile in type 2 diabetic women but not in men.Semantic proximity Read ↗

Association of metabolic parameters and rs726344 in FNDC5 with serum irisin concentrations.Semantic proximity Read ↗

Irisin expression and FNDC5 (rs3480) gene polymorphism in type 2 diabetic patients with and without CAD.Semantic proximity Read ↗

RS3480 Polymorphism of FNDC5/Irisin Is Associated with Type 2 Diabetes Mellitus in Maya-Mestizo Women.Semantic proximity Read ↗

FNDC5 (irisin) gene and exceptional longevity: a functional replication study with rs16835198 and rs726344 SNPs.Semantic proximity Read ↗

Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity.Semantic proximity Read ↗

Role and Functions of Irisin: A Perspective on Recent Developments and Neurodegenerative DiseasesSemantic proximity Read ↗

Fibronectin Type III Domain-Containing Protein 5 rs3480 A>G Polymorphism, Irisin, and Liver Fibrosis in Patients With Nonalcoholic Fatty Liver Disease.Semantic proximity Read ↗

Chemerin, Visfatin, Omentin-1 and Their Gene Polymorphisms Associated With Diabetes Associated Chronic Kidney DiseaseSemantic proximity Read ↗

NEAT1: A Novel Long Non-coding RNA Involved in Mediating Type 2 Diabetes and its Various ComplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.