Article
A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease.
PloS one - 1 Jan 2015
Khan Wasim, Aguilar Carlos, Kiddle Steven J, Doyle Orla, Thambisetty Madhav, Muehlboeck Sebastian, Sattlecker Martina, Newhouse Stephen, Lovestone Simon, Dobson Richard, Giampietro Vincent, Westman Eric, Simmons Andrew
Abstract excerpt
In this exploratory neuroimaging-proteomic study, we aimed to identify CSF proteins associated with AD and test their prognostic ability for disease classification and MCI to AD conversion prediction. Our study sample consisted of 295 subjects with CSF multi-analyte panel data and MRI at baseline downloaded from ADNI. Firstly, we tested the statistical effects of CSF proteins (n = 83) to measures of brain...
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