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Plasma proteomic signatures predict dementia and cognitive impairment

1 Jan 2020

Abstract excerpt

INTRODUCTION: Biomarker discovery of dementia and cognitive impairment is important to gather insight into mechanisms underlying the pathogenesis of these conditions. METHODS: In 997 adults from the InCHIANTI study, we assessed the association of 1301 plasma proteins with dementia and cognitive impairment. Validation was conducted in two Alzheimer's disease (AD) case-control studies as well as endophenotypes of...

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PMID: 32607407
DOI: 10.1002/trc2.12018

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