Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset.

PloS one - 1 Jan 2012

Johnstone Daniel, Milward Elizabeth A, Berretta Regina, Moscato Pablo

Abstract excerpt

BACKGROUND: Recent Alzheimer's disease (AD) research has focused on finding biomarkers to identify disease at the pre-clinical stage of mild cognitive impairment (MCI), allowing treatment to be initiated before irreversible damage occurs. Many studies have examined brain imaging or cerebrospinal fluid but there is also growing interest in blood biomarkers. The Alzheimer's Disease Neuroimaging Initiative (ADNI)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Proteins

Share to Cognitive Dysfunction

Share to Early Diagnosis

Share to Multivariate Analysis

Share to Proteome

Share to Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 22485168
DOI: 10.1371/journal.pone.0034341
PMCID: PMC3317783

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset.PMID 22485168Read ↗

Identification of Novel Biomarkers for Alzheimer’s Disease and Related Dementias Using Unbiased Plasma ProteomicsSemantic proximity Read ↗

Integrative analyses of neuroimaging, clinical, and multi-omics data identified meaningful Alzheimer’s disease progression subtypesSemantic proximity Read ↗

Blood-Based RNA Biomarkers and Machine Learning Approaches for Alzheimer’s DiseaseSemantic proximity Read ↗

High-sensitivity plasma proteomics reveals disease-specific signatures and predictive biomarkers of Alzheimer’s disease phenotypes in a large mixed dementia cohortSemantic proximity Read ↗

Predicting Alzheimer’s Disease with Multi-Omic Data: A Systematic ReviewSemantic proximity Read ↗

Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomicsSemantic proximity Read ↗

Revealing heterogeneity of brain imaging phenotypes in Alzheimer’s disease based on unsupervised clustering of blood marker profilesSemantic proximity Read ↗

Novel Plasma Protein Biomarkers: A Time-Dependent predictive model for Alzheimer's DiseaseSemantic proximity Read ↗

Large‐scale plasma proteomic profiling identifies a high‐performance biomarker panel for Alzheimer's disease screening and stagingSemantic proximity Read ↗

CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease.Semantic proximity Read ↗

Unified epigenomic, transcriptomic, proteomic, and metabolomic taxonomy of Alzheimer’s disease progression and heterogeneitySemantic proximity Read ↗

Proteomic Signatures of Neuropathological Alterations in Alzheimer’s Disease: Insights from the Bio-Hermes StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.