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Article

Co-evolution of the MHC class I and KIR gene families in rhesus macaques: ancestry and plasticity.

Immunological reviews - 1 Sept 2015

de Groot Natasja G, Blokhuis Jeroen H, Otting Nel, Doxiadis Gaby G M, Bontrop Ronald E

Abstract excerpt

Researchers dealing with the human leukocyte antigen (HLA) class I and killer immunoglobulin receptor (KIR) multi-gene families in humans are often wary of the complex and seemingly different situation that is encountered regarding these gene families in Old World monkeys. For the sake of comparison, the well-defined and thoroughly studied situation in humans has been taken as a reference. In macaques, both the...

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Identifiers

PMID: 26284481
DOI: 10.1111/imr.12313
PMCID: PMC4544828

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Source receipt: pubmed, retrieved 7 Sept 2026.

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