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Article

Unparalleled Rapid Evolution of KIR Genes in Rhesus and Cynomolgus Macaque Populations.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2020

Bruijnesteijn Jesse, de Groot Nanine, van der Wiel Marit K H, Otting Nel, de Vos-Rouweler Annemiek J M, de Groot Natasja G, Bontrop Ronald E

Abstract excerpt

The killer cell Ig-like receptors (KIR) modulate immune responses through interactions with MHC class I molecules. The KIR region in large cohorts of rhesus and cynomolgus macaque populations were characterized, and the experimental design enabled the definition of a considerable number of alleles (n = 576) and haplotypes, which are highly variable with regard to architecture. Although high levels of polymorphism...

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Source

Identifiers

PMID: 32111732
DOI: 10.4049/jimmunol.1901140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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