Article
Forearm vasodilator reactivity in healthy male carriers of the 3q22.3 rs9818870 polymorphism.
Microvascular research - 1 Nov 2015
Aschauer Stefan, Brunner Martin, Wolzt Michael, Haslacher Helmuth, Ristl Robin, Müller Markus
Abstract excerpt
BACKGROUND: A genome wide association study has identified a robust risk locus for cardiovascular disease on 3q22.3. However, the mechanisms by which the [C]/[T] polymorphism rs9818870 increases cardiovascular risk are unknown. This forearm blood flow (FBF) study addressed the question if the genetic association with cardiovascular disease in patients is preceded by incipient vasodilator impairment in young,...
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