Article
AMI is associated with polymorphisms in the NOS3 and FGB but not in PAI-1 genes in young adults.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2007
Sampaio Marcelo Ferraz, Hirata Mario Hiroyuki, Hirata Rosario Dominguez Crespo, Santos Fabiana Cristina Pereira, Picciotti Raffaella, Luchessi André Ducati, de Quateli Doi Sonia, Armaganijan Dikran, Batlouni Michel
Abstract excerpt
BACKGROUND: We investigated the relationship between NOS3, FGB and PAI-1 polymorphisms and endothelial dysfunction and risk factors for acute myocardial infarction (AMI) in young adults. METHODS: Endothelial function was measured by response to flow mediated vasodilation (FMV) and induced by nitrate (FMN). Biochemical parameters were measured by standard enzymatic methods and plasma total nitrate was analyzed by...
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