Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of Genetic Variation in PDE3A on Endothelial Function and Stroke.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2020

Traylor Matthew, Amin Al Olama Ali, Lyytikäinen Leo-Pekka, Marini Sandro, Chung Jaeyoon, Malik Rainer, Dichgans Martin, Kähönen Mika, Lehtimäki Terho, Anderson Christopher D, Raitakari Olli T, Markus Hugh S

Abstract excerpt

We aimed to characterize the genetics of endothelial function and how this influences risk for cardiovascular diseases such as ischemic stroke. We integrated genetic data from a study of ultrasound flow-mediated dilatation of brachial artery in adolescents from ALSPAC (Avon Longitudinal Study of Parents and Children; n=5214) with a study of ischemic stroke (MEGASTROKE: n=60 341 cases and 452 969 controls) to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Ischemia
Share to Cyclic Nucleotide Phosphodiesterases, Type 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to Follow-Up Studies

Share to Hypertension

Share to Pregnancy

Share to Pregnancy Complications, Cardiovascular

Share to Vasodilation

Source

Open in PubMed Open full text

Identifiers

PMID: 31865795
DOI: 10.1161/HYPERTENSIONAHA.119.13513
PMCID: PMC7055937

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of Genetic Variation in PDE3A on Endothelial Function and Stroke.PMID 31865795Read ↗

Sex-Specific Genetic Variants are Associated With Coronary Endothelial Dysfunction.Semantic proximity Read ↗

Phosphodiesterase 3A and Arterial Hypertension.Semantic proximity Read ↗

A genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamicsSemantic proximity Read ↗

Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamicsSemantic proximity Read ↗

A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.Semantic proximity Read ↗

Relation of candidate genes that encode for endothelial function to migraine and stroke: the Stroke Prevention in Young Women study.Semantic proximity Read ↗

The gene encoding phosphodiesterase 4D confers risk of ischemic stroke.Semantic proximity Read ↗

Common genetic variation at the endothelial nitric oxide synthase locus and relations to brachial artery vasodilator function in the community.Semantic proximity Read ↗

Advancing stroke therapeutics through genetic understanding.Semantic proximity Read ↗

Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis.Semantic proximity Read ↗

Stroke Genetics – Focus on PDE4D GeneSemantic proximity Read ↗

Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.