Article
Up-regulation of PSMB4 is associated with neuronal apoptosis after neuroinflammation induced by lipopolysaccharide.
Journal of molecular histology - 1 Dec 2015
Shi Jiansheng, Liu Xiaorong, Xu Changde, Ge Jianbin, Ren Jianbing, Wang Jun, Song Xinjian, Dai Shirong, Tao Weidong, Lu Hongjian
Abstract excerpt
Proteasomes are major intracellular extralysosomal organelle for protein degradation and a central source of antigenic peptides in the endogenous pathway. Proteasome beta-4 subunit (PSMB4) was recently identified as potential cancer driver genes in several tumors. However, information regarding its regulation and possible function in the central nervous system is still limited. The present study was designed to...
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