Article
Genotyping of Single Nucleotide Polymorphisms in DNA Isolated from Serum Using Sequenom MassARRAY Technology.
PloS one - 1 Jan 2015
Clendenen Tess V, Rendleman Justin, Ge Wenzhen, Koenig Karen L, Wirgin Isaac, Currie Diane, Shore Roy E, Kirchhoff Tomas, Zeleniuch-Jacquotte Anne
Abstract excerpt
BACKGROUND: Large epidemiologic studies have the potential to make valuable contributions to the assessment of gene-environment interactions because they prospectively collected detailed exposure data. Some of these studies, however, have only serum or plasma samples as a low quantity source of DNA. METHODS: We examined whether DNA isolated from serum can be used to reliably and accurately genotype single...
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