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Article

Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays.

PLoS genetics - 29 Aug 2008

Homer Nils, Szelinger Szabolcs, Redman Margot, Duggan David, Tembe Waibhav, Muehling Jill, Pearson John V, Stephan Dietrich A, Nelson Stanley F, Craig David W

Abstract excerpt

We use high-density single nucleotide polymorphism (SNP) genotyping microarrays to demonstrate the ability to accurately and robustly determine whether individuals are in a complex genomic DNA mixture. We first develop a theoretical framework for detecting an individual's presence within a mixtur...

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Identifiers

PMID: 18769715
DOI: 10.1371/journal.pgen.1000167
PMCID: PMC2516199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18769715-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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