Article
FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans.
PloS one - 1 Jan 2015
Taferner Andrea, Pircher Haymo, Koziel Rafal, von Grafenstein Susanne, Baraldo Giorgia, Palikaras Konstantinos, Liedl Klaus R, Tavernarakis Nektarios, Jansen-Dürr Pidder
Abstract excerpt
The fumarylacetoacetate hydrolase (FAH) protein superfamily of metabolic enzymes comprises a diverse set of enzymatic functions, including ß-diketone hydrolases, decarboxylases, and isomerases. Of note, the FAH superfamily includes many prokaryotic members with very distinct functions that lack homologs in eukaryotes. A prokaryotic member of the FAH superfamily, referred to as Cg1458, was shown to encode a...
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