Article
Comparative Analysis of Experimental Methods to Quantify Animal Activity in Caenorhabditis elegans Models of Mitochondrial Disease.
Journal of visualized experiments : JoVE - 4 Apr 2021
Lavorato Manuela, Mathew Neal D, Shah Nina, Nakamaru-Ogiso Eiko, Falk Marni J
Abstract excerpt
Caenorhabditis elegans is widely recognized for its central utility as a translational animal model to efficiently interrogate mechanisms and therapies of diverse human diseases. Worms are particularly well-suited for high-throughput genetic and drug screens to gain deeper insight into therapeutic targets and therapies by exploiting their fast development cycle, large brood size, short lifespan, microscopic...
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