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Article

Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 6 Sept 2016

Zhang Xinxing, Li Kunhua, Jones Rachel A, Bruner Steven D, Butcher Rebecca A

Abstract excerpt

Caenorhabditis elegans secretes ascarosides as pheromones to communicate with other worms and to coordinate the development and behavior of the population. Peroxisomal β-oxidation cycles shorten the side chains of ascaroside precursors to produce the short-chain ascaroside pheromones. Acyl-CoA oxidases, which catalyze the first step in these β-oxidation cycles, have different side chain-length specificities and...

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Identifiers

PMID: 27551084
DOI: 10.1073/pnas.1608262113
PMCID: PMC5018750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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