Article
Chromosomal copy number alterations for associations of ductal carcinoma in situ with invasive breast cancer.
Breast cancer research : BCR - 13 Aug 2015
Afghahi Anosheh, Forgó Erna, Mitani Aya A, Desai Manisha, Varma Sushama, Seto Tina, Rigdon Joseph, Jensen Kristin C, Troxell Megan L, Gomez Scarlett Lin, Das Amar K, Beck Andrew H, Kurian Allison W, West Robert B
Abstract excerpt
INTRODUCTION: Screening mammography has contributed to a significant increase in the diagnosis of ductal carcinoma in situ (DCIS), raising concerns about overdiagnosis and overtreatment. Building on prior observations from lineage evolution analysis, we examined whether measuring genomic features of DCIS would predict association with invasive breast carcinoma (IBC). The long-term goal is to enhance standard...
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