Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Molecular Portrait of High-Grade Ductal Carcinoma In Situ.

Cancer research - 15 Sept 2015

Abba Martin C, Gong Ting, Lu Yue, Lee Jaeho, Zhong Yi, Lacunza Ezequiel, Butti Matias, Takata Yoko, Gaddis Sally, Shen Jianjun, Estecio Marcos R, Sahin Aysegul A, Aldaz C Marcelo

Abstract excerpt

Ductal carcinoma in situ (DCIS) is a noninvasive precursor lesion to invasive breast carcinoma. We still have no understanding on why only some DCIS lesions evolve to invasive cancer whereas others appear not to do so during the life span of the patient. Here, we performed full exome (tumor vs. matching normal), transcriptome, and methylome analysis of 30 pure high-grade DCIS (HG-DCIS) and 10 normal breast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation, T-Lymphocyte
Share to Breast

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Intraductal, Noninfiltrating

Share to CTLA-4 Antigen

Share to Genes, Neoplasm

Share to Lymphocytes, Tumor-Infiltrating

Share to RNA, Neoplasm

Share to RNA, Untranslated

Source

Open in PubMed Open full text

Identifiers

PMID: 26249178
DOI: 10.1158/0008-5472.CAN-15-0506
PMCID: PMC4768486

Genes

ATM
CDH1
CTLA4
ERBB2
FOXP3
GATA3
HOXA5
TBX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Molecular Portrait of High-Grade Ductal Carcinoma In Situ.PMID 26249178Read ↗

Multi-omics portrait of ductal carcinoma in situ in young women.Semantic proximity Read ↗

Tumor microenvironmental determinants of high-risk DCIS progressionSemantic proximity Read ↗

Genomic Alterations during the In Situ to Invasive Ductal Breast Carcinoma Transition Shaped by the Immune SystemSemantic proximity Read ↗

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breastSemantic proximity Read ↗

Multi-omic profiling of simultaneous ductal carcinoma in situ and invasive breast cancer.Semantic proximity Read ↗

Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer.Semantic proximity Read ↗

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.Semantic proximity Read ↗

Mutational landscape of pure ductal carcinoma in situ and associations with disease prognosis and response to radiotherapySemantic proximity Read ↗

Tumor microenvironmental determinants of high-risk DCIS progressionSemantic proximity Read ↗

Mutational landscape of pure ductal carcinoma in situ and associations with disease prognosis and response to radiotherapySemantic proximity Read ↗

Cellular stemness identifies high-risk ductal carcinoma <i>in situ</i> and offers a therapeutic interception opportunitySemantic proximity Read ↗

Progression from ductal carcinoma <i>in situ</i> to invasive breast cancer: RevisitedSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.